首页> 外国专利> Composition comprising DDMP group soyasaponin for preventing or treating obesity or lipid related metabolic disease

Composition comprising DDMP group soyasaponin for preventing or treating obesity or lipid related metabolic disease

机译:包含DDMP基大豆皂苷的组合物,用于预防或治疗肥胖或脂质相关的代谢性疾病

摘要

Provided is a composition containing soyasaponin combined with DDMP (2,3-dihydro-2,5-dihydroxy-6-methyl-4H-pyran-4-one) as an active ingredient for preventing or treating obesity or lipid related metabolic diseases. The soyasaponin combined with the DDMP according to the present invention effectively inhibits the differentiation of preadipocytes to adipocytes and lipid accumulation occurring in the differentiation of preadipocytes to adipocytes and downregulates the expression of transcription factors related to the differentiation of preadipocytes to adipocytes. Thus, the soyasaponin combined with the DDMP according to the present invention can be useful for preventing or treating the obesity and lipid related metabolic diseases including fatty liver, type 2 diabetes, hyperlipidemia, cardiovascular disease, arteriosclerosis, and lipid related metabolic syndrome.
机译:提供了一种组合物,其包含大豆皂苷与DDMP(2,3-二氢-2,5-二羟基-6-甲基-4H-吡喃-4-酮)组合作为预防或治疗肥胖或脂质相关代谢疾病的活性成分。根据本发明的大豆皂苷与DDMP的组合有效地抑制了前脂肪细胞向脂肪细胞的分化以及在前脂肪细胞向脂肪细胞的分化中发生的脂质蓄积,并且下调了与前脂肪细胞向脂肪细胞的分化有关的转录因子的表达。因此,根据本发明的大豆皂苷与DDMP的组合可用于预防或治疗肥胖和脂质相关的代谢性疾病,包括脂肪肝,2型糖尿病,高脂血症,心血管疾病,动脉硬化和脂质相关的代谢综合症。

著录项

  • 公开/公告号KR101448116B1

    专利类型

  • 公开/公告日2014-10-08

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20120106515

  • 申请日2012-09-25

  • 分类号A61K31/015;A61K31/704;A61K31/35;A61P3/04;

  • 国家 KR

  • 入库时间 2022-08-21 15:40:01

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