BIMATOPROST AND THYMOLOL SOLUTIONS NOT CONTAINING CONSERVANTS

摘要

1. The composition of bimatoprost and timolol, not containing preservatives, to reduce intraocular pressure in humans, containing the following composition: approximately 0.03% w / v bimatoprost; approximately 0.5% timolol; approximately 0.268% w / v sodium phosphate dibasic heptahydrate; approximately 0.014% citric acid monohydrate; approximately 0.68% sodium chloride and water, and having a pH of 7.3.2. The composition of bimatoprost and timolol, not containing the preservatives according to claim 1 for reducing intraocular pressure in humans, containing the following composition: approximately 0.03% w / v bimatoprost; approximately 0.5% timolol; approximately 0.268% w / v sodium phosphate dibasic heptahydrate; approximately 0.014% citric acid monohydrate; approximately 0.68% sodium chloride and water, where the pH is 7.3.3. A solution of bimatoprost and timolol containing no preservatives according to claim 2, characterized in that timolol is timolol maleate 0.68% w / v. 4. The composition of bimatoprost and timolol according to claim 1, characterized in that it is a solution applicable for the treatment of glaucoma. The composition of bimatoprost and timolol according to claim 1, characterized in that it is contained in the form of disposable kits. The bimatoprost and timolol composition according to claim 1, characterized in that it is applied once a day to each eye. The bimatoprost and timolol composition according to claim 1, characterized in that it is applied twice a day to each eye. Compositions of bimatoprost and timolol according to claim 1, characterized in that it has a greater bioavailability of bimatoprost and timolol for each patient's eye with less side effects than bimatoprost and timolol with benzalkonium chloride as a preservative. The composition according to claim 1, excellent