APPLICATION OF Razagilin for the treatment of olfactory dysfunction

摘要

1. A method of treating a symptom of olfactory dysfunction in a subject suffering from olfactory dysfunction, comprising: a) determining the subject as suffering from olfactory dysfunction, and b) periodically administering to the subject thus determined an amount of R (+) - N-propargyl-1-aminoindan or its pharmaceutically an acceptable salt effective to treat a subject. 2. The method of claim 1, wherein the subject is a subject without Parkinson's disease. A method for reducing the progression of olfactory dysfunction in a subject without Parkinson’s disease suffering from olfactory dysfunction, comprising periodically administering to the subject an amount of R (+) - N-propargyl-1-aminoindan or a pharmaceutically acceptable salt thereof effective to reduce the progression of olfactory dysfunction in a subject without Parkinson's disease. 4. A method of inhibiting olfactory function loss in a subject without Parkinson's disease, comprising periodically administering to the subject an amount of R (+) - N-propargyl-1-aminoindan or a pharmaceutically acceptable salt thereof effective to inhibit olfactory function loss in a subject without Parkinson's disease. The method according to claim 1, wherein the amount of R (+) - N-propargyl-1-aminoindan or its pharmaceutically acceptable salt is from 0.01 mg to 5 mg per day. The method according to claim 5, wherein the amount of R (+) - N-propargyl-1-aminoindan or its pharmaceutically acceptable salt is 0.5 mg per day. The method of claim 5, wherein the amount of R (+) - N-propargyl-1-aminoindan or a pharmaceutically acceptable salt thereof is 2 mg per day. The method according to claim 5, in which the amount of R (+) - N-propargyl-1-aminoindan or its pharmaceutically acceptable salt is