HYDROPHIL CHROMATOGRAPHY COLUMN DEVICE AND ENRICHMENT DEVICE WITH SOLID-PHASE EXTRACTION FOR PREPARATION OF SAMPLES AND ANALYSIS OF PESTICIDES

摘要

1. A method for preparing samples and analyzing pesticides in samples, characterized by the steps of: (a) introducing a sample dissolved in a solvent with a predominantly low water content and / or a non-polar solvent into a column (14) for hydrophilic chromatography with a solvent with a predominantly low water content and / or non-polar solvent, (b) enrichment of at least most of the pesticides contained in the sample in the enrichment device (22) with solid-phase extraction, (c) supply of a part of the sample enriched with pesticides in the enrichment Ohm device with solid-phase extraction, in the opposite direction from the enrichment device with solid-phase extraction through a second chromatographic column with a solvent with a predominantly high water content and / or polar solvent by switching the valve block after the selected enrichment time, and (d) detecting separated in the second chromatographic column sample components. 2. The method according to claim 1, characterized in that a part of the sample stream, which during the selected time of enrichment flows through the enrichment device (22) with solid-phase extraction, is directly detected. The method according to claim 1, characterized in that in the second switching position of the valve block (20, 24), the pump (12) regenerates and / or cleans the chromatographic column (14) for hydrophilic chromatography. The method according to claim 1, characterized in that the column (14) for hydrophilic chromatography during the part of the analysis time in the second switching position is regenerated using the pump (18) on the mass spectrometer (32), and for the remaining part of the analysis time�