EUKARYOTIC HOST CELL FOR EXPRESSION OF DARBEPOETIN, EXPRESSION VECTOR AND METHOD OF PRODUCTION OF DARBEPOETIN ALFA

摘要

FIELD: biotechnology.;SUBSTANCE: expression vectors are claimed designed to express human darbepoetin. The host cells are proposed, containing the claimed vectors. The method of production of human darbepoetin-α from the culture medium of the proposed cell is claimed. The optimised gene of darbepoetin is proposed.;EFFECT: invention enables to obtain darbepoetin alpha - an analogue of recombinant human erythropoietin.;14 cl, 9 dwg, 3 tbl, 5 ex