首页> 外国专利> USE OF EPIGALLOCATECHIN GALLATE AS AN ANTIVIRAL AGENT FOR HEPATITIS C VIRUS INFECTIONS

USE OF EPIGALLOCATECHIN GALLATE AS AN ANTIVIRAL AGENT FOR HEPATITIS C VIRUS INFECTIONS

机译:使用没食子儿茶素加仑特作为抗丙型肝炎病毒感染的抗病毒药物

摘要

The present invention relates to a flavonoid compound having the formula I, where R3, R5 and/or R7 is a group having the formula II, or R1 and R2 are both OH groups, or to one of the pharmaceutically acceptable salts or esters thereof, for use as an antiviral agent in the treatment and/or prevention of a hepatitis C virus (HCV) infection. The invention also relates to an ex vivo method for reducing the infectivity of HCV or for inactivating HCV, including a step of contacting said hepatitis C virus with a compound having the formula (I).
机译:本发明涉及具有式I的类黄酮化合物,或其药学上可接受的盐或酯之一,其中R 3,R 5和/或R 7为具有式II的基团,或R 1和R 2均为OH基。在治疗和/或预防丙型肝炎病毒(HCV)感染中用作抗病毒药。本发明还涉及用于降低HCV感染性或使HCV失活的离体方法,包括使所述丙型肝炎病毒与具有式(I)的化合物接触的步骤。

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