Gene expression profile algorithms and tests to quantify the prognosis of prostate cancer

摘要

The present invention provides an algorithm-based molecular assay comprising measuring the expression level of a gene, or co-expressed gene thereof, from a biological sample taken from a prostate cancer patient. In order to calculate a quantitative score useful in predicting the likelihood of clinical outcome in prostate cancer patients, the genes can be classified into functional gene subsets. The application includes measurement of the expression level of one or more genes or gene subsets from a biological sample taken from a prostate cancer patient, and analysis of the measured expression level, whereby the likelihood of clinical outcome Disclosed are molecular assays that provide information regarding.