sitaxsentan derivative

摘要

Equation (1-1) or compound or a pharmacologically acceptable salt thereof represented by the formula (1-2), while retaining the primary efficacy included in sitaxentan, have an inhibitory effect improved CYP. [Formula 1] [In the formula, ^{R 1} means a halogen atom or the like, ^{R 2} means a methyl group, ^{R 3}_means a _{C 1-6} alkyl group, M is ## STR2 ## It is represented by I mean the group, and the like. ]