首页> 外国专利> RADIOLABELED ANALOG(S) OF COMPOUND 0118 AND USE THEREOF IN CONNECTION WITH PET AND/OR SPECT IMAGING TO DETERMINE WHETHER A PHARMACEUTICAL CONTAINING COMPOUND 0118 IS A CANDIDATE CANCER TREATMENT FOR A PATIENT

RADIOLABELED ANALOG(S) OF COMPOUND 0118 AND USE THEREOF IN CONNECTION WITH PET AND/OR SPECT IMAGING TO DETERMINE WHETHER A PHARMACEUTICAL CONTAINING COMPOUND 0118 IS A CANDIDATE CANCER TREATMENT FOR A PATIENT

机译:化合物0118的放射性标记类似物,并与PET和/或SPECT成像结合使用以确定是否含有药物的化合物0118是对患者的候选癌症治疗方法

摘要

A method for determining whether compound 0118 is a candidate treatment for a patient includes processing, via a processor, image data of tissue of interest of a patient including a cancer to determine whether a radiolabeled analog of compound 0118 is present in the tissue of interest represented in the image data and generating a signal indicating that compound 0118 is a candidate treatment for the patient in response to the determining that the radiolabeled analog of compound 0118 is present in a predetermined amount in the tissue of interest represented in the image data, wherein the presence of the radiolabeled analog of compound 0118 in the tissue of interest indicates presence of a sub-type of cancer having a galectin-1 molecular target, which is a sub-type of treatable by compound 0118.
机译:一种确定化合物0118是否为患者的候选疗法的方法,包括通过处理器处理包括癌症在内的患者感兴趣组织的图像数据,以确定所代表的感兴趣组织中是否存在化合物0118的放射性标记类似物响应于确定在图像数据中表示的目标组织中存在预定量的化合物0118的放射性标记类似物,并响应于确定图像中包含化合物0118是患者的候选治疗的信号,其中感兴趣的组织中存在化合物0118的放射性标记类似物表示存在具有半乳糖凝集素1分子靶标的癌症亚型,这是可通过化合物0118治疗的亚型。

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