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Methods for screening candidate agents for modulating prorenin and renin, assays for detecting prorenin and antibodies
Methods for screening candidate agents for modulating prorenin and renin, assays for detecting prorenin and antibodies
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机译:筛选调节肾素和肾素的候选药物的方法,检测肾素和抗体的试验
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摘要
The present invention relates to antibodies that bind to prorenin. In particular, the invention relates to monoclonal antibodies that bind to prorenin and inhibit the activation of prorenin. The antibodies of the invention are useful for screening for candidate agents that inhibit the activation of prorenin and candidate agents the modulate the activity of renin. The antibodies are also useful as diagnostics and for treating disease states.
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