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Human antibodies against Pseudomonas aeruginosa LPS derived from transgenic xenomouse
Human antibodies against Pseudomonas aeruginosa LPS derived from transgenic xenomouse
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机译:人类源自转基因异位鼠的铜绿假单胞菌 I> LPS抗体
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摘要
The invention described herein provides for human antibodies produced in non-human animals that specifically bind to Pseudomonas aeruginosa Lipopolysaccharide (LPS). The invention further provides methods for making the antibodies in a non-human animal, expression of the antibodies in cell lines including hybridomas and recombinant host cell systems. Also provided are kits and pharmaceutical compositions comprising the antibodies and methods of treating or preventing pseudomonas infection by administering to a patient the pharmaceutical compositions described herein.
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