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CD127 expression inversely correlates with FoxP3 and suppressive function of CD4+ Tregs
CD127 expression inversely correlates with FoxP3 and suppressive function of CD4+ Tregs
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机译:CD127表达与FoxP3和CD4 + Sup> Tregs的抑制功能呈负相关
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摘要
The invention provides methods of isolating CD127lo/− immunosuppressive regulatory T cells which can be greatly enriched for FoxP3, methods of expanding the isolated cells, pharmaceutical compositions of such cells, and methods of their use in the treatment of autoimmune and other immune system mediated disorders.
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机译:本发明提供了可为FoxP3大量富集的CD127 lo /- Sup>免疫抑制调节性T细胞的分离方法,扩增分离的细胞的方法,此类细胞的药物组合物及其在治疗中的使用方法自身免疫和其他免疫系统介导的疾病。
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