首页> 外国专利> Method of preventing and/or treating a neurodegenerative disease by administering an extract of Lycoris chejuensis and/or a compound isolated therefrom

Method of preventing and/or treating a neurodegenerative disease by administering an extract of Lycoris chejuensis and/or a compound isolated therefrom

机译：通过施用 Lycoris chejuensis 和/或从中分离出的化合物的提取物预防和/或治疗神经退行性疾病的方法

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摘要

Provided are novel use of an extract of Lycoris chejuensis or a compound isolated therefrom for inhibition of β-amyloid production and/or prevention, improvement and/or treatment of a neurodegenerative disease, more specifically a β-amyloid production inhibitor, and/or a composition for prevention or treatment of a neurodegenerative disease containing one or more kinds selected from the group consisting of an extract of Lycoris chejuensis, and/or dihydrolycoricidine, 2-methoxypancracine, lycoricidine, and/or lycoricidinol, as an active ingredient; a method for inhibiting β-amyloid production, and/or preventing and/or treating a neurodegenerative disease using the same; and, a method for preparing the same. 展开▼

机译：提供了 Lycoris chejuensis 的提取物或从其分离的化合物的新用途，其用于抑制β-淀粉样蛋白的产生和/或预防，改善和/或治疗神经退行性疾病，更具体地说是β-淀粉样蛋白。产生抑制剂，和/或用于预防或治疗神经退行性疾病的组合物，其包含一种或多种选自 Lycoris chejuensis 的提取物和/或二氢可可可啶，2-甲氧基Pancracine，Lycoricidine ，和/或麦角甾醇作为有效成分;一种抑制β淀粉样蛋白产生和/或预防和/或治疗神经变性疾病的方法;以及其制备方法。展开▼

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公开/公告号US9044501B2

专利类型

公开/公告日2015-06-02

原文格式PDF

申请/专利权人 HYUN-OK YANG;HAK-CHEOL KWON;JIN-SOO PARK;SUNG-KWON CHUNG;MYUNG-SOO KIM;
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申请/专利号US20090607972

发明设计人 HYUN-OK YANG;HAK-CHEOL KWON;JIN-SOO PARK;SUNG-KWON CHUNG;MYUNG-SOO KIM;
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申请日2009-10-28

分类号A61K36/896;A61K31/4741;

国家 US

入库时间 2022-08-21 15:18:48

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3. Method of preventing and/or treating a neurodegenerative disease by administering an extract of Lycoris chejuensis and/or a compound isolated therefrom [P] . 美国专利： US2010227851A1 . 2010-09-09

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机译：用于预防和/或治疗包含莱氏乳杆菌提取物和/或分离的复方茶的神经退行性疾病的组合物

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5. Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances [J] . Xiaoqian Niu, Jiejian Chen, Jianqing Gao 亚洲药物制剂科学(英文) . 2019,第005期

6. 7-Deoxy- trans-dihydronarciclasine isolated from Lycoris chejuensis inhibits neuroinflammation in experimental models [J] . Dong Zhao, Lijun Zhang, Hyun Ok Yang IBRO Reports . 2019,第3期

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8. Effect of Lycoris chejuensis and Its Active Components on Experimental Models of Alzheimer's Disease [J] . Kim Joonki, Park Yurim, Chun Yoon Sun, Journal of Agricultural and Food Chemistry . 2015,第31期

9. Analysis of photobiomodulation therapy conditions used to treat neurodegenerative brain diseases [C] . Sungkyoo Lim Conference on Mechanisms and Techniques in Photodynamic Therapy and Photobiomodulation . 2021

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12. 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