Use of a synergistic combination of neratinib and capecitabine in the manufacture of medicaments

摘要

A combination of a HKI-272 compound and a capecitabine compound in the treatment of a neoplasm is provided. Regimens, kits, and methods for treatment of neoplasm, including breast cancer including metastatic breast cancer, and lung cancer, using this combination, optionally in combination with other anti-neoplastic agents, or immune modulators are also described.