首页> 外国专利> Novel process for the preparation of (1r,5s)-n-3-amino-1(cyclobutylmethyl)-2,3-dioxopropyl-3-2(s)-(1,1-dimethylethyl)aminocarbonylamino-3,3-dimethyl-1-oxobutyl-6,6-dimethyl-3-azabicyclo3.1.0hexan-2(s)-carboxamide

Novel process for the preparation of (1r,5s)-n-3-amino-1(cyclobutylmethyl)-2,3-dioxopropyl-3-2(s)-(1,1-dimethylethyl)aminocarbonylamino-3,3-dimethyl-1-oxobutyl-6,6-dimethyl-3-azabicyclo3.1.0hexan-2(s)-carboxamide

机译:制备(1r,5s)-n- [3-氨基-1(环丁基甲基)-2,3-二氧丙基] -3- [2(s)-[[[(1,1-二甲基乙基)氨基]的新方法[羰基]氨基] -3,3-二甲基-1-氧丁基] -6,6-二甲基-3-氮杂双环[3.1.0] hexan-2(s)-羧酰胺

摘要

The present invention relates to a process for the preparation (lR,5S)-N-[3-amino-1 -(cyclobutylmethyl)-2,3 -dioxopropyl]-3 - [2(S)- [ [ [(1,1 -dimethylethyl)amino] carbonyl]amino]-3,3-dimethyl-l-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide represented by structural formula-1. The present invention also provides novel intermediate compounds.
机译:本发明涉及一种制备(1R,5S)-N- [3-氨基-1-(环丁基甲基)-2,3-二氧丙基] -3- [2(S)-[[[(1,由结构式-1表示的1-二甲基乙基)氨基]羰基]氨基] -3,3-二甲基-1-氧丁基] -6,6-二甲基-3-氮杂双环[3.1.0]己二(S)-羧酰胺。本发明还提供了新颖的中间体化合物。

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