'stable pharmaceutical composition of active fragments of basic fibroblast growth factor (bfgf) for treating vitiligo and process of preparation thereof'

摘要

The present invention relates to a clear, stable pharmaceutical composition in the form of solution for topical administration in the treatment of Vitiligo comprising: Active fragment of bFGF in the range of 0.02 to 0.5 % w/w; at least one penetration enhancing agent in the range of 10-40 % w/v; at least one non-ionic surfactant in the range of 0.001% to 2.0 % w/v and acidulated medium in the range of 5 to 20 % v/v, using sodium acetate in solution having pH 4.00 to 5.00; Wherein said pharmaceutical composition does not contain a glycol.