Amide substituted with Heterocyclic compounds useful as modulators of the responses of Interleukin 12 (il-12), Interleukin 3 (IL - 23) and / or interferon (IFN Alpha (alpha))

摘要

The Invention relates to compounds having the formula I: or a stereoisomer or a pharmaceutically acceptable Salt thereof, wherein R1, R2, R3, R4 and R5 are as defined herein, are useful for the Modulation of il-12 and il-23 and / or ifnalfa acting on Tyk - 2 to generate the Inhibition of signal transduction