New methyl esters of N-substituted amino acid (aryl or alkyl)methyl-phosphonic and a method for preparing methyl esters of N-substituted amino acid (aryl or alkyl)methyl-phosphonic

摘要

the subject of the invention are new methyl esters n - substituted amino acids (arylo - or alkyl) metylofosfonowych presented general model 1 in which r1 is a group ferrocenylowu0105 or 2 - tienylowu0105 or cykloheksylowu0105 and r2 means the benzyl moiety or 4 - metylofenylowu0105,used as substances with characteristics herbicydalnych and cytotoxic and process for the production of methyl esters of n - substituted amino acids (arylo - or alkyl) metylofosfonowych, by the reaction between acetaldehyde, amine and fosforynem dwumetylowym.reaction synthesis runs as an equal between acetaldehyde of the general formula (2), in which r1 is a radical fenylowu0105 or 2 - furylowu0105 or 2 - tienylowu0105 or ferrocenylowu0105 or fenyloetenylowu0105 and cykloheksylowu0105, fosforynem dimetylowym and amine of the general formula r2 - nh2, which radical r2 means the benzyl moiety or 4 - metylofenylowu0105, outerconstant magnetic field of induction in the range from 0.25 to 1.25 t t, maintaining temperature of 350 to 355 k, a polar organic solvent.