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CYTOPLASMIC TAIL MODIFICATIONS TO BOOST SURFACE EXPRESSION AND IMMUNOGENICITY OF ENVELOPE GLYCOPROTEINS
CYTOPLASMIC TAIL MODIFICATIONS TO BOOST SURFACE EXPRESSION AND IMMUNOGENICITY OF ENVELOPE GLYCOPROTEINS
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机译:细胞膜尾部修饰修饰包膜糖蛋白的表面表达和免疫原性
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摘要
The invention provides compositions and methods for enhanced expression of a viral envelope protein. The invention provides a composition comprising a cytoplasmic tail modification to enhance surface expression of both HIV and non-HIV viral envelope proteins as wells as other membrane associated proteins resulting in increased immunogenicity.
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