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METHOD FOR INCLUSION OF DRUG IN MEMBRANE VESICLE THROUGH CELL MODIFICATION USING MEMBRANE FUSOGENIC LIPOSOME AND DRUG DELIVERY METHOD USING SAME
METHOD FOR INCLUSION OF DRUG IN MEMBRANE VESICLE THROUGH CELL MODIFICATION USING MEMBRANE FUSOGENIC LIPOSOME AND DRUG DELIVERY METHOD USING SAME
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机译:膜融合脂质体通过细胞修饰法将膜中的药物包含在内的方法及使用该方法的药物递送方法
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摘要
The present invention relates to a membrane vesicle in which a prepared drug is included using a membrane fusogenic liposome (MFL), a membrane vesicle preparation method, and a drug delivery method using the membrane vesicle. Specifically, the membrane vesicle of the present invention allows hydrophilic and hydrophobic drugs to be simultaneously included therein, is isolated from a cell to facilitate more efficient and selective drug delivery to neighboring cells, and is safe as a nanomaterial derived from a living body, and a step for directly entrapping the drug in the membrane vesicle is unnecessary. Therefore, the membrane vesicle can be effectively used for preventing and treating a variety of cancers and degenerative diseases in which the membrane vesicle is known to play an important role.
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