COMPOSITIONS AND METHODS FOR BLOOD BIOMARKER ANALYSIS FOR PREDICTING PSYCHOSIS RISK IN PERSONS WITH ATTENUATED PSYCHOSIS RISK SYNDROME

摘要

Provided herein are methods for identifying a risk of developing a psychotic disorder in a subject. In some embodiments, the methods include isolating serum and/or plasma from a subject who meets clinical criteria for elevated risk of psychosis; quantifying levels of expression in the serum and/or plasma for a plurality of gene products; combining the quantified levels of expression to create a summary measure of expression; and comparing the summary measure of expression for the subject to one or more standards; wherein the comprising step identifies a risk of developing a psychotic disorder in the subject. Also provided are methods for identifying whether or not a subject is developing a psychotic disorder, kits for use in performing the disclosed methods, and non-transitory computer readable medium having stored thereon computer executable instructions that can be used to perform the disclosed methods.