METHOD predicting the severity of depressive disorders in men with coronary heart disease

摘要

A method of predicting the severity of depressive disorders in men with coronary heart disease (CHD) of setting a temporary and structural connection between coronary heart disease and symptoms of depression using clinical approaches and determining polymorphism 5-HTTLPR gene serotonin transporter, characterized in that after the connection between CHD and symptoms of depression measured trait anxiety levels via Spielberger-Hanin test and level of trait anxiety scores below 45 further comprising determining polymorph zmy - 1438A / G serotonin receptor gene Type 2A and Val66Met gene neurotrophic cerebral factor, after which patients are carriers of the short allele (S) polymorphism 5-HTTLPR, allele G polymorphism - 1438A / G and genotype ValVal polymorphism Val66Met, predict depression development severe.