METHOD OF EVALUATING IMPAIRMENT OF HAEMOGLOBIN OXYGENATION IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN IN THIRD TRIMESTER OF GESTATION WITH REDUCTION OF GLUCONEOGENESIS AT BACKGROUND OF CYTOMEGALOVIRAL INFECTION AGGRAVATION

摘要

FIELD: medicine.;SUBSTANCE: invention deals with a method of evaluating a threat of hypoxia formation in pregnant women with the aggravation of the cytomegaloviral infection in the third trimester of gestation. The essence of the method: in peripheral blood a titre of antibodies to cytomegalovirus is determined, the activity of phosphoenolpyruvate dehydrogenase is determined by the histochemical method, the content of discocytes, echinocytes, target-shaped erythrocytes, degenerative forms of erythrocytes, oxyhaemoglobine quantity are determined in peripheral blood. If the titre of antibodies to cytomegalovirus is 1:1600, detection of the reduction of phosphoenolpyruvate dehydrogenase activity to 12.0±0.09 c. u.: reduction of discocytes in peripheral blood to 74.0±1.3%, increase of the number of echinocytes to 7.0-0.2, target-shaped erythrocytes to 8.5±0.3%, degenerative forms of erythrocytes to 10.5±0.15% and reduction of the oxyhaemoglobine quantity to 92.0±1.6% a threat of formation of haemic hypoxia is evaluated.;EFFECT: improvement of the method of the threat evaluation.;2 dwg