METHOD OF COMPLEX TREATMENT AND PREVENTION OF RECURRENCES OF MUSCULAR-NON-INVASIVE FORMS OF URINARY BLADDER CANCER

摘要

FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to oncology and oncological surgery, and can be used for complex endourethral treatment and prevention of recurrences of muscular non-invasive forms of urinary bladder cancer. For this purpose bilpolar transurethral resection of urinary bladder tumour in physiological solution is performed. After that, on 25-30 day once per week carried out is 1.5-2 month long induction course of intravesical immunotherapy with medicinal composition, which is prepared immediately before introduction into urinary bladder by mechanical mixing of 100-120 mg of BCG Imuron vaccine and 10 g of Tizol gel in 50 g of physiological solution. Time of exposure of medicinal composition in urinary bladder constitutes 30 minutes. 1 month after break in case of absence of tumour recurrence and satisfactory tolerance of treatment first course of supporting intravesical therapy with said medicinal composition is carried out once monthly with 12 month duration. When first course is completed, 1-month break is made. In case of absence of tumour recurrence and satisfactory tolerance of treatment second course of supporting intravesical therapy is carried out once monthly with 12 month duration.EFFECT: method provides increase of recurrence-free period duration and improvement of patients' life quality with reduction of treatment toxicity and reduction of complications of performed drug therapy.2 dwg, 5 tbl, 2 ex