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A BREATH TEST FOR THE DIAGNOSIS OF HELICOBACTER PYLORI INFECTION
A BREATH TEST FOR THE DIAGNOSIS OF HELICOBACTER PYLORI INFECTION
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机译:诊断幽门螺杆菌感染的呼吸试验
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摘要
A method for diagnosing a Helicobacter pylori infection in a patient treated with proton-pump-inhibitors (PPIs) comprising the steps of administering to the patient an acid, collecting a first breath sample, administering to the patient 13C-labeled urea, waiting for a time of 10 to 60 minutes, thereafter collecting a second breath sample from the patient, measuring the content of 13C in the CO2 of the first and second sample and determination of a 13C/12C ratio by mass spectroscopy in the respective samples characterized in that a difference Δδ of the 13C/12C ratio of the first breath sample and 13C/12C ratio of the second breath sample is calculated and the value of the difference in the range of 2 to 2,9% indicates the presence of a H. pylori infection in the patient.
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机译:诊断用质子泵抑制剂(PPI)治疗的患者的幽门螺杆菌感染的方法,该方法包括以下步骤:向患者施用酸,收集第一次呼吸样本,向患者施用 13 Sup>用C标记的尿素,等待10到60分钟,然后从患者那里收集第二次呼吸样品,并测量其CO 2 Sub>中的 13 Sup> C含量在第一样品和第二样品中,通过质谱法分别测定 13 Sup> C / 12 Sup> C比,其特征在于, 13 Aup>的差异Δδ计算第一个呼吸样本的Sup> C / 12 Sup> C比率和第二个呼吸样本的 13 Sup> C / 12 Sup> C比率,并将其值差异的2%至2,9%表明患者中存在幽门螺杆菌感染。
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