CUT-POINT IN PTEN PROTEIN EXPRESSION THAT ACCURATELY IDENTIFIES TUMORS AND PREDICTS DRUG RESPONSE TO PAN-ErbB INHIBITOR

摘要

PROBLEM TO BE SOLVED: To provide a cut point in PTEN protein expression that accurately identifies breast cancers and predicts a drug response to a PAN-ErbB inhibitor.SOLUTION: A method comprises: obtaining a tumor cell and a non-tumorigenic cell from a breast cancer patient; performing quantitative measurement of PTEN protein expression in the tumor cell and the non-tumorigenic cell; calculating a normalized PTEN protein expression score by comparing these two quantitative measurements of PTEN protein expression.SELECTED DRAWING: None