首页>
外国专利>
COMPOSITION HAVING CONJUGATE OF PIGMENT AND POLYETHYLENE GLYCOL, AND ADDITIVES; AND PHOTOACOUSTIC-IMAGING CONTRAST AGENT HAVING COMPOSITION THE SAME
COMPOSITION HAVING CONJUGATE OF PIGMENT AND POLYETHYLENE GLYCOL, AND ADDITIVES; AND PHOTOACOUSTIC-IMAGING CONTRAST AGENT HAVING COMPOSITION THE SAME
展开▼
机译:具有颜料和聚乙烯乙二醇及添加剂共轭的组合物;和光声造影剂组成相同
展开▼
页面导航
摘要
著录项
相似文献
摘要
PROBLEM TO BE SOLVED: To provide a photoacoustic-imaging contrast agent which has high clustering properties to a tumor, leaves little residue in blood, and is capable of administration into blood.;SOLUTION: The invention provides a photoacoustic-imaging contrast agent consisting of a conjugate (A) of a pigment and a polyethylene glycol, the pigment having, as a basic skeleton, a bisindole structure constructed by binding a methine chain to a five-membered ring comprising N at both ends of the methine chain; and additives (B), such as cyclodextrin, which interact with the conjugate. After the administration into blood, the aggregate of (A) and (B) is transferred from blood to a tumor, while the aggregate remaining in blood is dissolved and discharged from the body.;SELECTED DRAWING: Figure 1;COPYRIGHT: (C)2016,JPO&INPIT
展开▼