Expression vectors for establishment of highly productive cell comprising a drug selection fusion gene

摘要

PROBLEM TO BE SOLVED: To provide an expression vector effective for establishing a transformed cell expressing a target protein gene at high levels.;SOLUTION: The expression vector comprises: (1) an expression cassette containing a drug-selective marker gene and a dihydrofolic acid reductase gene present adjoining the drug-selective marker gene; (2) a gene expression-stabilizing element; and (3) a target protein gene expression cassette.;COPYRIGHT: (C)2013,JPO&INPIT