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Method for detecting risk of liver cancer in a person infected with hepatitis C virus

机译:在丙型肝炎病毒感染者中检测肝癌风险的方法

摘要

PROBLEM TO BE SOLVED: To provide a method for detecting risks of progressing to cirrhosis of the liver or liver cancer in patients infected by hepatitis C virus (HCV), and to provide a guide for positively selecting a preventive treatment in patients infected by hepatitis C virus.SOLUTION: There is provided a method for detecting risks of liver cancer comprising detection of variation of arginine on a position of seventieth in an amino acid sequence of HCV core region contained in a sample collected from a human infected by genotype 1b HCV, and chronologically quantifying the variation on the same human, wherein comparing the quantitative value with the quantitative value of just before and in the case of increasing the variation means a signal of transfer into liver cancer.
机译:解决的问题:提供一种检测丙型肝炎病毒(HCV)感染患者发展为肝硬化或肝癌的风险的方法,并为积极选择丙型肝炎感染患者的预防性治疗提供指导病毒。解决方案:提供了一种检测肝癌风险的方法,该方法包括检测从基因型1b HCV感染的人收集的样品中所含HCV核心区域氨基酸序列中第70位精氨酸的变化,以及按时间顺序对同一个人的变异进行定量,其中将定量值与变异增加前和定量增加时的定量值进行比较意味着转移到肝癌的信号。

著录项

  • 公开/公告号JP5960509B2

    专利类型

  • 公开/公告日2016-08-02

    原文格式PDF

  • 申请/专利权人 熊田 博光;芥田 憲夫;

    申请/专利号JP20120122496

  • 发明设计人 熊田 博光;芥田 憲夫;

    申请日2012-05-29

  • 分类号C12Q1/68;G01N33/68;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 14:42:36

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