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Culture substrate for inducing osteoblast differentiation, method for inducing osteoblast differentiation, and method for producing osteoblast

机译:用于诱导成骨细胞分化的培养基质,用于诱导成骨细胞分化的方法以及用于制备成骨细胞的方法

摘要

PROBLEM TO BE SOLVED: To provide a method for efficiently and potently inducing the differentiation of osteoblast cells as compared to the conventional methods.SOLUTION: There is provided a culture substrate for differentiation induction of osteoblast cells which is covered with a fish-derived collagen and has a contact surface to mesenchymal stem cells. There is also provided a method for inducing the differentiation of osteoblast cells which contains a fish-derived collagen contact process in which a cell culture substrate covered with a fish-derived collagen is brought into contact with mesenchymal stem cells, or a method for producing osteoblast cells which contains a fish-derived collagen culture process in which mesenchymal stem cells are cultured by using a cell culture substrate covered with a fish-derived collagen.
机译:解决的问题:提供一种与常规方法相比有效且有效地诱导成骨细胞分化的方法。解决方案:提供了一种用于成骨细胞分化诱导的培养基质,其上覆盖有鱼衍生的胶原蛋白和与间充质干细胞有接触面。还提供了一种诱导成骨细胞分化的方法,该方法包含鱼来源的胶原蛋白接触过程,其中将覆盖有鱼来源的胶原蛋白的细胞培养底物与间充质干细胞接触,或产生成骨细胞的方法。含有鱼来源的胶原蛋白培养过程的细胞,其中间充质干细胞通过使用覆盖有鱼来源的胶原蛋白的细胞培养底物进行培养。

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