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Anti-tumor agent and therapeutic effect prediction method for KRAS gene variant colorectal cancer patients
Anti-tumor agent and therapeutic effect prediction method for KRAS gene variant colorectal cancer patients
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机译:KRAS基因变异大肠癌患者的抗肿瘤药及疗效预测方法
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摘要
This invention provides a method for predicting a therapeutic effect of chemotherapy that uses an antitumor agent comprising ±,±,±-trifluorothymidine and 5-chloro-6-(1-(2-iminopyrrolidinyl)methyl)uracil hydrochloride at a molar ratio of 1:0.5 on a colorectal cancer patient, the method comprising: (1) detecting the presence or absence of KRAS gene mutation in a biological sample obtained from the patient; and (2) predicting that the patient is likely to sufficiently respond to the chemotherapy, when KRAS gene mutation is detected in Step (1).
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