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COMPOSITIONS AND METHODS RELATED TO RECOMBINANT ANTIBODIES TO HISTONE POSTTRANSLATIONAL MODIFICATIONS
COMPOSITIONS AND METHODS RELATED TO RECOMBINANT ANTIBODIES TO HISTONE POSTTRANSLATIONAL MODIFICATIONS
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机译:与组蛋白翻译后修饰的重组抗体有关的组合物和方法
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摘要
Embodiments concern compositions and methods involving recombinant antibodies to histone post-translational modifications. The invention provides compositions and methods for histone methyltransferase assays. In certain embodiments, the compositions and methods involve a recombinant antibody that binds histone H3 fragment harboring biomarkers such as H3K9me3 mark, H3K4me3 mark, H3K36me3 mark, H3K27me3, H3K9me3 and H3S10phos or a recombinant antibody that binds histone H4 fragment harboring H4K20me3 mark.
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