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Materials and Methods Useful For Affecting Tumor Cell Growth, Migration and Invasion
Materials and Methods Useful For Affecting Tumor Cell Growth, Migration and Invasion
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机译:可用于影响肿瘤细胞生长,迁移和侵袭的材料和方法
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摘要
It is disclosed herein that miR-221 and miR-222 down-regulate PTEN and TIMP3 tumor suppressors, resulting in TRAIL resistance. The present invention provides research, diagnostic, and therapeutic tools and methods related to this discovery. Diagnostics, prognostics and treatments for human hepatocellular cancer and non-small cell lung carcinoma having a TRAIL resistance are particularly described herein.
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