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AGGREGATED CELL EVALUATION METHOD AND AGGREGATED CELL EVALUATION DEVICE

机译:融合细胞评价方法及融合细胞评价装置

摘要

An aggregated cell evaluation apparatus includes a laser light source, a speckle image acquisition unit, an SC calculation unit, an evaluation unit, and a memory unit. The speckle image acquisition unit acquires a two-dimensional speckle image by forward scattered light generated in aggregated cells by irradiation of the aggregated cells with laser light output from the laser light source. The SC calculation unit calculates a speckle contrast value Kn of a speckle image In at each time tn, determines a maximum value Kmax among the speckle contrast values K1 to KN, and normalizes the speckle contrast value Kn at each time tn by the maximum value Kmax to obtain a normalized speckle contrast value Kn′. The evaluation unit evaluates motion of the aggregated cells, based on the normalized speckle contrast value Kn′ at each time tn.
机译:聚合细胞评估设备包括激光光源,散斑图像获取单元,SC计算单元,评估单元和存储单元。斑点图像获取单元通过利用从激光源输出的激光照射聚集细胞而在聚集细胞中产生的前向散射光来获取二维斑点图像。 SC计算单元在每次t n 时计算斑点图像I n 的斑点对比度值K n ,确定最大值K <将散斑对比度值K 1 中的Sub> max 变换为K N ,并在每次标准化散斑对比度值K n t n ,取最大值K max ,得到标准化的散斑对比度值K n '。评估单元基于每个时间t n 的归一化散斑对比度值K n '评估聚合单元的运动。

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