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Process for the preparation of colesevelam hydrochloride
Process for the preparation of colesevelam hydrochloride
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机译:盐酸西乙威仑的制备方法
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摘要
A novel process of manufacturing colesevelam hydrochloride including the steps of alkylating polyallylamine with n-decylbromide and 6-bromohexyl trimethyl ammonium bromide, followed by cross-linking the alkylated polyallylamine with epichlorohydrin in an aqueous medium, and adding a suitable chloride ion source to obtain colesevelam hydrochloride.
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