It includes the pharmacological components of solid McDonald's scattering, and a process of forming dispersible sheets containing solid McDonald's

摘要

Claim 1: a Pharmaceutical composition in the form of a dispersible Tablet which comprises a Solid dispersion of 40 - or - (2 - hydroxy) - ethyl - Rapamycin, a disintegrating comprising cross-linked polyvinylpyrrolidone and Colloidal SILICON DIOXIDE, wherein the composition The comprises 1 to 5% Colloidal SILICON DIOXIDE by weight.Claim 8: a process for producing a dispersible Tablet which contains 40 - O - (2 - hydroxy) - ethyl - Rapamycin, characterized in that it comprises the preparation of Solid dispersion of 40 - or - (2 - hydroxy) - ethyl - Rapamycin, mixing the solid dispersion of 40 - or - (2 - hydroxy) ethyl Rapamycin co N a disintegrating comprising cross-linked polyvinylpyrrolidone and Colloidal SILICON DIOXIDE.Where the composition comprises 1 to 5% by weight of Colloidal SILICON DIOXIDE to form a Pharmaceutical Composition and compression of the pharmaceutical composition to form the dispersible tablet.