method for assessing and predicting an effect of a candidate for a therapeutic agent to treat alzheimer's disease or moderate cognitive impairment; method for diagnosing and assisting the diagnosis of alzheimer's disease or moderate cognitive impairment; and method for selecting a patient likely to benefit from a therapeutic effect of a candidate therapeutic agent to treat alzheimer's disease or moderate cognitive impairment

摘要

Desmosterol alone, the combination of desmosterol and amyloid beta, the combination of desmosterol and gelsolin and the combination of desmosterol, amyloid beta and gelsolin can be used as in-blood biomarkers for Alzheimer's disease or mild cognitive impairment. A method for evaluating the effect of a candidate for a therapeutic agent to treat Alzheimer's disease or mild cognitive impairment, a method for aiding the diagnosis of Alzheimer's disease or mild cognitive impairment, and a method for diagnosing Alzheimer's disease or mild cognitive impairment are provided in which the biomarkers are used.