variants of the major timothy grass phl p 1 allergen, their folding forms lm and hm, their uses and their preparation and purification processes, DNA molecule, recombinant DNA expression vector and its use, and pharmaceutical compositions

摘要

"variants of the main phl p1 allergen of timothy grass". The present invention relates to variants of the main phl1 Timothy grass allergen characterized by the fact that a hitherto un possible preparation of monomeric molecules which are soluble and stable in the physiological environment can be carried out with the help of of prokaryotic expression systems and subsequent purification thereof.