COMBINATION OF OXYCODON AND NALOXONE FOR THE TREATMENT OF PATIENTS IN PATIENTS SUFFERING FROM PAIN AND DISEASE THROUGH THE INTESTINAL DYSBIOSIS AND / OR INCREASING THE RISK OF INTESTINAL MICROROSOLCATION

摘要

The present invention relates to an oral dosage form containing oxycodone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for the treatment of pain in patients suffering from i) pain and at least one contributing disease) ii) wherein said at least one contributing the disease ii) leads to intestinal dysbiosis, or for treating pain in patients suffering from i) pain and at least one contributing to the disease iii) where at least one contributes her disease iii) increases the risk of translocation of intestinal microflora and consequently peritonitis, SIRS and / or sepsis.