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Composition for iontophoretic transdermal delivery of cationic active agents and use thereof as a component of a transdermal patch
Composition for iontophoretic transdermal delivery of cationic active agents and use thereof as a component of a transdermal patch
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机译:用于阳离子电渗透性递送阳离子活性剂的组合物及其作为透皮贴剂的成分的用途
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摘要
The invention relates to a composition for transdermal delivery, particularly iontophoretic transdermal delivery, of at least one cationic active agent or a salt thereof, said composition comprising said at least one cationic active agent or a salt thereof, at least one polyamine or/and polyamine salt, water or an aqueous solvent mixture, and optionally one or more additives. The invention further relates to the use of said composition as a component of a transdermal patch or of an iontophoretic transdermal patch, and to the use of said composition in a method for transdermally or iontophoretically administering cationic active agents, and to a method for determining the in vitro skin permeation properties of an active agent-containing iontophoretic composition.
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