OXIDIZED FRACTION OF EXTRACELLULAR DNA AS A BIOMARKER OF STRESS AND METHODS FOR USING THE SAME

摘要

The present invention relates to methods of treating and diagnosing oxidative damage in a subject comprising administering an agent that binds oxidized extracellular nucleic acid, and methods of treating diseases and conditions in a subject comprising administering an adjuvant therapy comprising an agent that binds oxidized extracellular nucleic acid. The oxidized fraction of extraceiluiar DMA can also be detected through electrochemical methods or by mass- spectrometry.