SYSTEMS AND METHODS FOR ENHANCING PLATELET BIOGENESIS AND EXTENDING PLATELET LIFESPAN, IN CIRCULATION AND STORAGE

摘要

The present disclosure is directed to systems and methods that can apply low level light (LLL) to platelets and/or platelet precursor cells. While not wishing to be bound by theory, it is believed that LLL can enhance the ATP synthesis by the mitochondria within the platelets and/or the platelet precursor cells to help enhance platelet biogenesis and extend the platelet lifespan. In some instances, LLL can facilitate in vitro and/or in vivo platelet biogenesis. In other instances, LLL can extend platelet lifespan in circulation. In still other instances, LLL can be employed to prolong the shelf-life of stored platelets.