首页> 外国专利> SOLID-PHASE SUPPORT, LIGAND-BONDING SOLID-PHASE SUPPORT, TARGET-SUBSTANCE DETECTING OR SEPARATING METHOD, AND METHOD OF MANUFACTURING SOLID-PHASE SUPPORT

SOLID-PHASE SUPPORT, LIGAND-BONDING SOLID-PHASE SUPPORT, TARGET-SUBSTANCE DETECTING OR SEPARATING METHOD, AND METHOD OF MANUFACTURING SOLID-PHASE SUPPORT

机译:固相支持,配体固相支持,目标物质检测或分离方法以及制造固相支持的方法

摘要

Provided is a solid-phase support that can be manufactured by means of a simple method, that is unlikely to exhibit non-specific adsorption, and that exhibits an excellent target-substance capturing capability when bonded with a ligand. The present invention is a solid-phase support characterized in that at least a solid-phase surface is formed of a copolymer including the following structural units (A) to (C): (A) a structural unit that is derived from monomers having zwitterion structures and that is contained at 1 to 35 % by mass relative to all structural units; (B) a structural unit that is derived from monomers having functional groups capable of chemically bonding with ligands and that is contained at 70 % or less by mass relative to all structural units; and (C) a structural unit that is derived from slightly water-soluble monomers having no functional group capable of chemically bonding with ligands.
机译:提供了一种固相载体,其可以通过简单的方法制造,不太可能表现出非特异性吸附,并且当与配体结合时表现出优异的靶物质捕获能力。本发明是一种固相载体,其特征在于,至少固相表面由包含以下结构单元(A)至(C)的共聚物形成:(A)衍生自具有两性离子单体的结构单元相对于所有结构单元,其含量为1-35%质量; (B)衍生自具有能够与配体化学键合的官能团的单体的结构单元,相对于所有结构单元,该结构单元的含量为70质量%以下。 (C)衍生自不具有能够与配体化学键合的官能团的微水溶性单体的结构单元。

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