The present disclosure discloses pharmaceutical compositions for the prevention or treatment of diseases associated with cerebral apoplexy or seizures comprising a substance targeting miR-203. The present disclosure also discloses markers and their uses that can be used in the diagnosis or prognosis measurement of diseases associated with cerebral apoplexy or seizures. The composition of the present invention is capable of restoring glycine receptors, unlike existing therapeutic agents that rely on a high-dose therapy, and is capable of fundamentally treating diseases related to various diseases such as epilepsy and seizures by lowering the expression level of glycine receptors have.
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