LENTIVIRAL VECTORS CONTAINING AN MHC CLASS I, MHC CLASS II OR 2 MICROGLOBULIN UPSTREAM PROMOTER SEQUENCE

摘要

The present invention relates to the insertion of MHC class I, MHC class II or beta 2 microglobulin upstream promoter sequences into lentivirus vectors to increase viral titers. The present invention encompasses methods of using these vectors, methods of making the vectors, and pharmaceutical uses.