The present invention relates to a pharmaceutical composition for inhibiting vascular smooth muscle cell proliferation or migration comprising a microRNA-365 activator, wherein microRNA-365 inhibits the expression of cyclin D1 in the G1 / S phase of the cell cycle, And can be used for preventing, diagnosing, or treating abnormal proliferation or migration diseases of vascular smooth muscle cells by inhibiting the formation of endothelium upon vascular injury.
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