Pyruvate kinase type M2 PKM2 Pharmaceutical composition for enhancing sensitivity to anticancer drugs comprising expression or activity inhibitor of PKM2 as an active ingredient

摘要

The present invention relates to a pharmaceutical composition for enhancing anticancer drug sensitivity and anticancer drugs containing an expression or activity inhibitor of PKM2 as an active ingredient, and a method for enhancing an anti-cancer effect. Since the PKM2 expression or activity inhibitor of the present invention has an effect of depleting PKM2 present in cancer cells and promoting apoptosis by the anticancer agent, the pharmaceutical composition and chemotherapeutic composition for enhancing the sensitivity of the anticancer agent, It can be usefully used for improving the effect.