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SYSTEM AND METHOD FOR DETECTION OF MARKERS OF CIRCULATING TOMOR CELL BASED ON GENE EXPRESSION FEATURE ANALYSIS

机译:基于基因表达特征分析的循环肿瘤细胞标志物检测系统及方法

摘要

A system for detecting a circulating tumor cell using a gene expression characteristic according to an embodiment of the present invention is a system for detecting a circulating tumor cell detection gene using a gene expression feature and includes a circulating tumor cell condition and a circulating tumor cell gene having normal blood cell condition A circulating tumor cell-associated gene selecting a circulating tumor cell-associated gene from the expression data, a survival assurance function for selecting a survival-proof circulating tumor cell-associated gene excluding the apoptosis-associated gene among the circulating tumor cell-associated genes, A cell identification method for selecting a cell-detectable gene from among the cancer-associated genes, a cancer-identifying gene selection method for selecting a cancer-related gene related to each cancer by cancer type, Binding to related genes To include existing genes circulating tumor cell detection gene selection identified the source as possible carcinogens circulating tumor cells detected by genetic type of cancer selected from the unit for.
机译:根据本发明实施方式的利用基因表达特征检测循环肿瘤细胞的系统是利用基因表达特征检测循环肿瘤细胞检测基因的系统,其包括循环肿瘤细胞状况和循环肿瘤细胞基因。具有正常血细胞状态的循环肿瘤细胞相关基因,从表达数据中选择循环肿瘤细胞相关基因,具有生存保障功能,用于在循环中从凋亡相关基因中选择不与生存相关的循环肿瘤细胞相关基因。肿瘤细胞相关基因,用于从癌症相关基因中选择细胞可检测基因的细胞鉴定方法,用于根据癌症类型选择与每种癌症相关的癌症相关基因的癌症鉴定基因选择方法,基因包括现有基因循环肿瘤细胞检测基因选择确定了可能的来源是循环肿瘤细胞中的致癌物,可通过从癌症的遗传类型中选择的单位进行检测。

著录项

  • 公开/公告号KR101605886B1

    专利类型

  • 公开/公告日2016-03-23

    原文格式PDF

  • 申请/专利权人 한국과학기술원;

    申请/专利号KR20140186461

  • 发明设计人 이관수;차기훈;

    申请日2014-12-22

  • 分类号G06F19/18;

  • 国家 KR

  • 入库时间 2022-08-21 14:12:47

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