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Lactobacillus casei 1- 2- Composition for Preventing Improving or Treating of 1-mediated Immune Disease or 2-mediated Immune Disease Comprising Extracts from Lactobacillus casei as an Active Ingredients
Lactobacillus casei 1- 2- Composition for Preventing Improving or Treating of 1-mediated Immune Disease or 2-mediated Immune Disease Comprising Extracts from Lactobacillus casei as an Active Ingredients
The present invention relates to a composition for preventing, ameliorating or treating a Th1-mediated immune disease or a Th2-mediated immune disease comprising Lactobacillus casei as an active ingredient. The Lactobacillus casei of the present invention activates regulatory T cells, increases IL-10 production, which is an anti-inflammatory cytokine, inhibits IL-12 production, which is an immunologically active cytokine, and decreases the amount of IgE antibody production, There is an advantage that it can be used as an anti-allergic composition and an anti-inflammatory composition for effectively controlling mediated immune diseases or Th2-mediated immune diseases.
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