5+2 14- Method for synthesizing azomethin ylide derivatives having excellent stability and method for synthesizing 14-diazepine derivatives using multicomponent 5+2 cycloaddition reaction

摘要

The present invention relates to a process for the preparation of a substituted pyridine represented by the formula (1) in the presence of a metal catalyst; And reacting a substituted 1-sulfonyl-1,2,3-triazole represented by the general formula (2) with an azomethine group represented by the general formula A method for preparing an azomethine ylide derivative, and a substituted pyridine represented by the formula (1) in the presence of a metal catalyst; Substituted 1-sulfonyl-1,2,3-triazole represented by the general formula (2); And a multicomponent [5 + 2] cyclization addition reaction step for reacting an alkyne represented by the general formula (4).